FcRn is mother’s milk to allergen tolerance | Allergy (and clinical immunology) | Scoop.it
From jem.rupress.org - December 11, 2017 12:11 PM
In this issue Ohsaki et al. (<https://doi.org/10.1084/jem.20171163>;) explain how breastfeeding can prevent the onset of food allergies in offspring by instructing T reg formation via neonatal Fc receptor (FcRn)–mediated transfer and uptake of allergen-containing IgG immune complexes (Ig-ICs) by gut dendritic cells (DCs).