Like many a great artist, the fortunes of Michelangelo Merisi da Caravaggio rose and fell dramatically. After his death, possibly from syphilis or murder, his influence spread across the continent as followers called Caravaggisti took his extreme use of chiaroscuro abroad. He influenced Rubens, Rembrandt, and Velázquez—indeed, the entire Baroque period in European art history probably would never have happened without him.