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What is epigenetic ageing, and can we control it — or even reverse it — with diet and exercise? - ABC News

What is epigenetic ageing, and can we control it — or even reverse it — with diet and exercise? - ABC News | Épigénétique | Scoop.it
"Project Blueprint" involves eating the same two meals every day, a regimented exercise routine and a structured sleep schedule. But can it really slow or reverse the ageing process?
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Discover now how this controversial American millionaire managed to reverse his aging thanks to epigenetics! 
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How Epigenetics & RNA Can Help Save the Honey Bees

How Epigenetics & RNA Can Help Save the Honey Bees | Épigénétique | Scoop.it
Honey bee populations worldwide are declining drastically, but a new study sheds light on how a transmissible RNAi pathway might be able to help honey bees become more resistant to pathogens and other threats.
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Honey bees: understanding autism & social behaviour

Honey bees: understanding autism & social behaviour | Épigénétique | Scoop.it
I will explain the social behaviour of—and between—autistic people and neurotypicals, using honey bees as an analogy. It will make sense soon, I promise!
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Researchers Find an Epigenetic Signature Linked With MIS-C

Researchers Find an Epigenetic Signature Linked With MIS-C | Épigénétique | Scoop.it
The genes identified in this signature organize the response of T-cells, the response of natural killer lymphocytes, or the complex factor of HLA-DRB1 antigens.
Tom Accart Lescarcelle's insight:
In the quest to understand the mysterious multisystem inflammatory syndrome in children (MIS-C) associated with SARS-CoV-2, researchers have uncovered an epigenetic signature named EPIMISC. This signature, identified in a cohort study comparing healthy children, children with COVID-19 without MIS-C, and children with MIS-C, sheds light on the altered immune response and viral activity control implicated in MIS-C development.
 The study, led by the Josep Carreras Leukemia Research Institute and the Bellvitge Biomedical Research Institute in Barcelona, suggests potential applications for early diagnosis and management of MIS-C, emphasizing the role of immune system hyperreactivity in severe outcomes…
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Epigenetic Drug Effective against Bladder Cancer in Mice

Epigenetic Drug Effective against Bladder Cancer in Mice | Épigénétique | Scoop.it
A new mouse study by researchers at Northwestern Medicine offers hope as it demonstrates an epigenetics drug currently being used for blood cancers and rare sarcomas may halt the growth of bladder cancer by activating the immune system.
Tom Accart Lescarcelle's insight:
In this recent study, researchers at Northwestern Medicine have discovered that an epigenetic drug, tazemetostat, initially developed for blood cancers and rare sarcomas, shows promise in halting the growth of bladder cancer in mice. Unlike traditional tumor inhibition, this drug activates the immune system, marking a paradigm shift in treating one of the most common solid tumors. Lead author Joshua Meeks highlights the drug's unique mechanism and its potential to enhance survival in advanced bladder cancer. The study underscores the role of epigenetic therapy in bladder cancer, with tazemetostat now undergoing clinical trials for late-stage bladder cancer patients, offering a new avenue for effective treatment.
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Alimentation et 1 000 premiers jours de vie | inrae.fr

Alimentation et 1 000 premiers jours de vie | inrae.fr | Épigénétique | Scoop.it
L'alimentation depuis la grossesse jusqu’aux 2 ans de l’enfant est une période déterminante pour son développement et sa santé.
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A new epigenetic brain defense against recurrence of opioid use

A new epigenetic brain defense against recurrence of opioid use | Épigénétique | Scoop.it
Substance use disorder (SUD) is an extremely difficult disorder to overcome, and many individuals with SUD return to regular use after repeated attempts to quit.
Tom Accart Lescarcelle's insight:
A recent research led by Dr. Christopher Cowan at the Medical University of South Carolina reveals a potential breakthrough in addressing substance use disorder (SUD), focusing on opioid addiction.
 The study identifies an epigenetic enzyme, histone deacetylase 5 (HDAC5), as a key player in limiting heroin-associated memories and drug-seeking behavior after a period of abstinence in rats. HDAC5, known for its role in gene expression regulation, has previously been linked to cocaine use. By manipulating HDAC5 levels, researchers observed a significant impact on heroin-seeking behavior, suggesting a crucial role in modulating drug-associated memories. Understanding these molecular mechanisms opens avenues for targeted therapies to treat SUD, providing hope for more effective interventions in addiction recovery.
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What is epigenetics? - Carlos Guerrero-Bosagna

View full lesson: http://ed.ted.com/lessons/how-the-choices-you-make-can-affect-your-genes-carlos-guerrero-bosagnaHere’s a conundrum: Identical twins origina...
Tom Accart Lescarcelle's insight:
Here is a short video to approach and learn about the epigenetic’s topic before going further ! (for those who aren’t already familiar with)
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