Here, the scientists report a strategy for constructing RNA-only nanodevices to evaluate complex logic in living cells. Their ribocomputing’ systems are composed of de-novo-designed parts and operate through predictable and designable base-pairing rules, allowing the effective in silico design of computing devices with prescribed configurations and functions in complex cellular environments.
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Here, the scientists report a strategy for constructing RNA-only nanodevices to evaluate complex logic in living cells. Their ribocomputing’ systems are composed of de-novo-designed parts and operate through predictable and designable base-pairing rules, allowing the effective in silico design of computing devices with prescribed configurations and functions in complex cellular environments.