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Scientists discover unknown virus in ‘throwaway’ DNA | University of Oxford

Scientists discover unknown virus in ‘throwaway’ DNA | University of Oxford | Bioscience News - GEG Tech top picks | Scoop.it
A chance discovery has opened up a new method of finding unknown viruses.
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In research published in the journal Virus Evolution, scientists from Oxford University’s Department of Zoology have revealed that Next-Generation Sequencing and its associated online DNA databases could be used in the field of viral discovery. They have developed algorithms that detect DNA from viruses that happen to be in the blood or tissue sample of the species studied. The research focused on fish genomes as an example, but the method could be used to identify viruses in a range of different species.

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Mobile Microscope Detects DNA Sequences 

Mobile Microscope Detects DNA Sequences  | Bioscience News - GEG Tech top picks | Scoop.it
Targeted DNA sequencing and in situmutation analysis using mobile phone microscopy
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Researchers have built a microscope that uses the camera on a cell phone to detect fluorescent products of DNA sequencing reactions in cells and tissues, according to a study published January 16th in Nature Communications. The mobile microscope can detect a point mutation in the KRAS gene that occurs in more than 30 percent of colon cancers.

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Marisol Touraine announced the creation of 12 genome sequencing centers

Marisol Touraine announced the creation of 12 genome sequencing centers | Bioscience News - GEG Tech top picks | Scoop.it
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The goal ? Commit France to the revolution in personalized medicine.

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23andMe Relaunches Consumer DNA Testing Service

23andMe Relaunches Consumer DNA Testing Service | Bioscience News - GEG Tech top picks | Scoop.it
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Consumer genetics testing company 23andMe said on Wednesday, 21th it was relaunching its personal DNA testing service with a limited menu of tests that have won the approval of the U.S. Food and Drug Administration.


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Computational analysis of cell-to-cell heterogeneity in single-cell RNA-sequencing data reveals hidden subpopulations of cells - Nature Biotechnology

Computational analysis of cell-to-cell heterogeneity in single-cell RNA-sequencing data reveals hidden subpopulations of cells - Nature Biotechnology | Bioscience News - GEG Tech top picks | Scoop.it
Hidden cell sub-populations are detected by accounting for confounding variation in the analysis of single-cell RNA-seq data.
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A new method helps scientists create a more accurate picture of gene expression in different cell types, and reveals hidden subtypes of cells.


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Mapping Large Numbers of Single Cell Genomes Simultaneously 

Mapping Large Numbers of Single Cell Genomes Simultaneously  | Bioscience News - GEG Tech top picks | Scoop.it
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This new study demonstrates a method of barcoding cells multiple times and then sequencing them. The method greatly expands the number of single cells that can be mapped. The findings from this study were published recently in Nature Methods in an article entitled “Sequencing Thousands of Single-Cell Genomes with Combinatorial Indexing.”

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The First DNA Sequencing in Space Could Happen This Summer

The First DNA Sequencing in Space Could Happen This Summer | Bioscience News - GEG Tech top picks | Scoop.it
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Kate Rubins, a virologist turned astronaut, heads to the ISS this month to monitor more than 250 experiments, including genetic sequencing

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Into the wild with DNA: using portable nanopore DNA sequencers to combat wildlife crime

Into the wild with DNA: using portable nanopore DNA sequencers to combat wildlife crime | Bioscience News - GEG Tech top picks | Scoop.it
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A team from the University of Leicester has been awarded a prize for their proposal to crack down on wildlife crime using a portable DNA sequencing device, the MinION - developed by Oxford Nanopore Technologies - to read the ‘barcode genes’ of animals affected by illegal trafficking. 

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The BabySeq Project

The BabySeq Project | Bioscience News - GEG Tech top picks | Scoop.it
Genome Sequence-Based Screening for Childhood Risk and Newborn Illness Principal Investigators: Robert C. Green and Alan H. Beggs Co-Principal Investigators: Peter Park, Heidi Rehm, Pankaj Agrawal,...
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This month, doctors in Boston will begin the BabySeq project, in which they will sequence yhe genomes of newborns to look for signs of diseases that begin in childhood.


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Resolving the complexity of the human genome using single-molecule sequencing : Nature : Nature Publishing Group

Resolving the complexity of the human genome using single-molecule sequencing : Nature : Nature Publishing Group | Bioscience News - GEG Tech top picks | Scoop.it



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To identify missing sequence and genetic variation, the scientists sequence and analyse a haploid human genome (CHM1) using single-molecule, real-time DNA sequencing. Their results suggest a greater complexity of the human genome in the form of variation of longer and more complex repetitive DNA that can now be largely resolved with the application of this longer-read sequencing technology.


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