The repurposing of a bacterial defence system known as CRISPR into a potent activator of gene expression in human cells enables powerful studies of gene function, as exemplified in cancer cells. This review summarize some key studies about the use of CRISPR to establish functions of gene, regulatory element and pathway.
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The repurposing of a bacterial defence system known as CRISPR into a potent activator of gene expression in human cells enables powerful studies of gene function, as exemplified in cancer cells. This review summarize some key studies about the use of CRISPR to establish functions of gene, regulatory element and pathway.
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