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Genetic Engineering Publications - GEG Tech top picks
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In this Report, The scientists present an efficient method for seamless correction of pF508del mutation in patient-specific induced pluripotent stem cells by gene edited homologous recombination. Gene edition has been performed by transcription activator-like effector nucleases (TALEN) and a homologous recombination donor vector which contains a PiggyBac transposon-based double selectable marker cassette.