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In the United States, one out of every 500 African American children have sickle cell disease (SCD), and SCD affects approximately 100,000 Americans. Significant advances in the treatment of this monogenetic disorder have failed to substantially extend the life expectancy of adults with SCD over...
Via Krishan Maggon
Considering the progress made in the management of sickle cell disease during the past 30 years, along with the excellent results obtained with hematopoietic stem cell transplantation (SCT), it is important to reexamine why, who, when and how to recommend allogeneic SCT in children with sickle...
Via Krishan Maggon
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LIGHTING
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In this podcast, Dr. Amanda Brandow and Dr. Eddy Lang discuss the clinical importance of ASH Guidelines on SCD, specifically the guideline opening April 10, 2019, for public comment, Sickle Cell Disease-Related Pain. To access and comment on these guidelines, visit www.hematology.org/guidelines-public-comment. The comment period will open April 10 and close May 13, 2019.
In this podcast, Dr. Amanda Brandow and Dr. Eddy Lang discuss the clinical importance of ASH Guidelines on SCD, specifically the guideline opening April 10, 2019, for public comment, Sickle Cell Disea
Children born with sickle cell disease in low-resource regions of the world often remain undiagnosed and therefore do not receive appropriate treatment.
Perspective from The New England Journal of Medicine — Sickle Cell Disease — A History of Progress and Peril
Acta Haematol. 2016 Jul 16;136(3):147-151. [Epub ahead of print]
J R Soc Med. 2016 Jun 20. pii: 0141076816651037. [Epub ahead of print]
When it comes to a devastating blood disorder, sometimes two wrongs make a right
Sickle cell disease is a hereditary blood disorder that affects red blood cells, distorting their natural disc shape into a crescent moon or “sickle” shape
Yahoo! Maktoob News 145750 sickle cell anemia cases in KSA Zawya (registration) RIYADH: A total of 9,417 sickle cell anemia cases were reported in the Kingdom over the past 10 years, bringing the number of people living with the inherited blood...
Hydroxyurea pills worked as well as transfusions in reducing stroke risk, researchers report
Review the Society's top Sickle Cell Disease research and training priorities for the next five years.
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Novartis will have the go-ahead to begin marketing Adakveo, the first targeted therapy for sickle cell disease.
Researchers explored patients', parents' and physicians' perspectives on the use of CRISPR-Cas9 gene-editing to reverse sickle cell disease.
Via Krishan Maggon
Dr. Osunkwo discusses the REACH Trial, which demonstrates the safety and efficacy of hydroxyurea use among children in four sub-Saharan African countries, and its implications for treating sickle cell disease.
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Researchers identify molecular glitch that causes animals’ blood cells to change shape
Via MRC press office
Original Article from The New England Journal of Medicine — Gene Therapy in a Patient with Sickle Cell Disease
Antioxid Redox Signal. 2016 Jul 8. [Epub ahead of print]
Sickle cell disease (SCD) is a group of inherited red blood cell disorders. Healthy red blood cells are round, and they move through small blood vessels to carry oxygen to all parts of the body.
Dr. Francis was credited with successfully using antibiotics to treat children with the disease 15 years before the effectiveness of those drugs was confirmed.
A promising new treatment for sickle cell anemia, developed by the National Institutes for Health and validated by a new study by the University of Illinois at Chicago, holds out the prospect of a cure for this chronic disease. Dr.
#CXNTop10 #10: REVIEW: Hematopoietic Stem Cell Transplantation for Sickle Cell Disease: State of the Science http://t.co/I4Fp80q0dd
Conclusive data show that hydroxyurea therapy offers safe and effective disease management of sickle cell anemia (SCA) and reduces the risk of stroke, prompting early termination by the National Heart Lung and Blood Institute (NHLBI) of a key...
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