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Researchers have reported the discovery of a crucial part of the biological clock in the brain: wiring that sets its accuracy to within a few minutes out of the 1440 minutes per day. This wiring uses the GABA (γ-amino-butyric acid) neurotransmitter to connect the individual cells of the biological clock in a fast network that changes strength with time of day.
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There is a large body of evidence to suggest that omega-3s are beneficial for brain health and heart health. A new study evaluated omega-3 supplements and their effect on cognitive performance. The findings supported established health benefits of these supplements.
The researchers concluded that supplementation with omega-3 polyunsaturated fatty acids (PUFA) could postpone the onset of metabolic disorders and associated declines in cognitive functioning.
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Karl Deisseroth, MD, PhD, a professor of bioengineering and of psychiatry and behavioral sciences at Stanford University, and postdoctoral scholar Melissa Warden, PhD, have isolated the neurons that carry the split-second decisions to act, from the higher brain to the brain stem. In doing so, they have provided insight into the causes of severe brain disorders such as depression.
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They might be caused by common medications used to treat insomnia, anxiety, itching or allergies, according to Dr. Cara Tannenbaum, Research Chair at the Institut universitaire de gériatrie de Montréal (IUGM, Montreal Geriatric University Institute) and Associate Professor of Medicine and Pharmacy at the University of Montreal (UdeM).
Up to 90 percent of people over the age of 65 take at least one prescription medication. Eighteen percent of people in this age group complain of memory problems and are found to have mild cognitive deficits. Research suggests there may be a link between the two.
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Mayo Clinic study in seniors finds that diets high in sugars and starches promote brain fog and dementia.
Correlations between carb intake and brain fog included: *Those with the highest carbohydrate intake relative to total fat and protein intake were 3.6 times likelier to develop MCI.
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Researchers compared vitamin E levels in Alzheimer's, mild cognitive impairment, and cognitively normal subjects.
Individuals with cognitive impairment or Alzheimer's had lower blood levels of vitamin E.
The study concluded that both disorders were associated with increased vitamin E damage. Low plasma tocopherols and tocotrienols levels are associated with increased odds of MCI and AD.
Neurobiol Aging. 2012 Oct;33(10):2282-90. Epub 2011 Dec 20.
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Memory performance on a word list, showing the SuperAgers performed significantly better than elderly controls.
Is loss of grey matter an automatic part of aging?
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In a recent study, maintaining high blood levels of caffeine appeared to help adults over 65 ward off Alzheimer's disease. The study participants started with mild cognitive impairment, but none of the participants with higher blood levels developed Alzheimer's during the 2-4 year period.
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A new trial is planned using pig cells implanted into the brain of Parkinson’s patients. These cells are intended to support the existing brain cells and help repair damaged nerve cells.
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This drug detects and quantifies a particular biological marker for Alzheimer’s. There is still no cure, and the drug is radioactive...
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A new technique for analyzing brain images may make it possible to predict the rate of progression and physical path of many degenerative brain diseases, using just one magnetic resonance imaging (MRI) image...
The technique also supports mounting evidence that dementias spread through the brain along specific neuronal pathways in the same manner as prion diseases."
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Getting shape and eating right have connections to the brain. And the whole package can help you stay in good health to enjoy a long quality of life.
Brain>>Eating
Exercise>>Brain Exercise can literally help you develop new brain cells, plus lead to increased willpower...
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"A cancer drug given to mice eliminates brain-damaging proteins, leading to improved cognition within days, but will it work in humans?"
This cancer drug, Bexarotene, has now been shown to increase levels of APoE. If ongoing study shows that it can increase levels of the E2 allele, that will be more promising for Alzheimer's treatment.
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A way to stimulate the brain’s natural defense mechanisms in people with Alzheimer’s disease has been discovered by researchers at Université Laval, CHU de Québec and pharmaceutical firm GlaxoSmithKline (GSK): a molecule known as MPL (monophosphoryl lipid A) that stimulates the activity of the brain’s immune cells.
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By turning off an immune system transmitter in mice with an Alzheimer’s-like condition, scientists have been able to greatly reduce the accumulation of an abnormal protein known as amyloid-ß in the animals’ brains.
Previous studies have shown that the protein plays a central role in Alzheimer’s disease. It is hoped that the research may ultimately point the way towards a method of preventing or treating the disease in humans.
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In neurodegenerative diseases, the choroid plexus and CPECs age prematurely, resulting in reduced CSF formation and decreased ability to flush out the plaque-forming proteins that are a hallmark of Alzheimer’s.
Transplant studies have provided proof of concept for CPEC-based therapies. However, such therapies have been hindered by the inability to expand or generate CPECs in culture.
“Our method is promising, because for the first time we can use stem cells to create large amounts of these epithelial cells, which could be utilized in different ways to treat neurodegenerative diseases,” said Monuki, an associate professor of pathology & laboratory medicine and developmental & cell biology at UCI.
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Açai fruit fed to aged rats reversed age-related cognitive and motor declines, a study conducted through Tufts University has found.
The rats who were fed açai performed significantly better on the cognitive and motor skill tests than their counterparts on a standard diet.
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Brainy beverage: study reveals how green tea boosts brain cell production to aid memory | KurzweilAI
EGCG can easily pass through the blood-brain barrier and reach the functional parts of the brain. While EGCG is a known antioxidant, the team believes it could also have a beneficial effect against age-related degenerative diseases.
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People who keep their teeth and gums healthy with regular brushing may have a lower risk of developing dementia later in life, according to a U.S. study.
Researchers at the University of California who followed nearly 5,500 elderly people over an 18-year-period found that those who reported brushing their teeth less than once a day were up to 65 percent more likely to develop dementia than those who brushed daily.
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(Reuters) - Taking a week off from nearly all mental and physical activity - including television, talking on the phone and visiting with friends - was linked with improved mental performance and fewer...
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It’s pretty much that simple.
Sugar reduces plasticity in the brain and makes it harder to learn and remember. From children growing up with high levels of fructose, to college students with snacks and studies, to adults using sweetened convenient foods and trying to get ahead, everyone can be held back by sugar.
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A study at the University of Toronto on a handful of people with suspected mild Alzheimer’s disease (AD) suggests that a device that sends continuous electrical impulses to specific “memory” regions of the brain appears to increase neuronal activity.
Results of the study using deep brain stimulation, a therapy already used in some patients with Parkinson’s disease and depression, may offer hope for at least some with AD, an intractable disease with no cure.
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A new long term berry study found that just a couple of servings a week could delay memory decline...
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UCLA researchers have identified the intracellular mechanisms regulated by vitamin D3 that may help the body clear the brain of amyloid beta, the main...
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The first study to specifically examine the effects of the Mediterranean diet found benefits to the brain.
Coming out in this month's issue of Archives of Neurology, a new study indicates that the eating pattern typically called the 'Mediterranean diet,' might help protect the small blood vessels in the brain. This could mean less stroke and less memory loss for people that eat within these guidelines, though the results are an association only and not considered hard proof.
People who ate more monounsaturated fats (such as in olive oil) had the best brain scans.
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