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Activating an enzyme known to play a role in the anti-aging benefits of calorie restriction delays the loss of brain cells and preserves cognitive function in mice, according to a study published in the May 22 issue of The Journal of Neuroscience.
The findings could one day guide researchers to discover drug alternatives that slow the progress of age-associated impairments in the brain.
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New research suggests it might reduce the risk of developing cancer, dementia and other diseases.
Ray and Terry's 's insight:
Caloric Restriction is one of the pillars of our TRANSCEND health program.
Kat Carroll's curator insight,
March 9, 2013 2:24 PM
Fasting while providing liver support and protein fractions is not 'true' fasting but intelligent 'fasting'. The liver is driven by nutrients and toxins escorted out on proteins. Seems wise to give toxins a clear bowel, a method of binding and then transporting them out vs. allowing them to recirculate as potentially more dangerous metabolites. The brain and gut reflect one another so no surprise what cleanses and rebalances the GI tract will do the same for the brain -
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The red wine compound resveratrol could help to extend life and may even help to battle obesity by 'moderating' food consumption, according to new research ... in bees.
The findings showed that bees given resveratrol consumed less food and lived up to 38% longer.
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People who restrict their caloric intake in an effort to live longer have hearts that function more like those in people who are 20 years younger.
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Hara Hachi Bu mean to eat only until you are 80% full. The Okinawans control their caloric intake with this cultural idea. This means they naturally restrict calories by 20%. Caloric restriction is the most powerful known method of life extension that we know so far.
"Okinawa, Japan has been deemed one of the Blue Zones’
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According to a study carried out by a team led by María Blasco, the director of the Spanish National Cancer Research Centre (CNIO) and head of the Telomeres and Telomerase Group, a sustained lowering of food intake over time results in an increase of telomere length -- the ends of chromosomes -- in adult mice, which has a protective effect on the DNA and genetic material.
Ray and Terry's 's insight:
Caloric restriction is step 6 of the Transcend program. Moderate CR (10%) is manageable and easier to sustain over the long term.
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To survey previously uncharted territory, a team of researchers at UW-Madison has created an “atlas” that maps more than 1,500 unique landmarks within mitochondria that could provide clues to the metabolic connections between caloric restriction and aging.
The map, as well as the techniques used to create it, could lead to a better understanding of how cell metabolism is rewired in some cancers, age-related diseases and metabolic conditions such as diabetes.
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Vaccines and antibiotics may someday join caloric restriction or bariatric surgery as a way to regulate weight gain, according to a new study focused on the interactions between diet, the bacteria that live in the bowel, and the immune system.
Researchers examined the complicated relationship between the immune system, gut bacteria, digestion and obesity. They showed how weight gain requires not just caloric overload but also a delicate, adjustable -- and transmissible -- interplay between intestinal microbes and the immune response.
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People with asthma may one day receive an unconventional prescription for their condition: eat less.
Caloric Restriction (CR) has been studied for years as a method for life extension. This has been proven to work in animal studies, but the results are still unclear in human-- mainly because human lifespan is so much longer than animal lifespan that an adequate study is difficult to engineer.
Now we have evidence that CR may help lower risk of diseases, from asthma to cancer and even Alzheimer's.
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"New study finds that short fasting cycles can work as well as chemotherapy, and the two combined greatly improve survival."
Caloric Restriction (CR) is currently the most successful method we know for extending lifespan. But extreme CR tends to make you gaunt-looking and pretty unhappy. That's no good. We recommend moderate CR, cutting 10% of your caloric intake. This will still benefit your body.
To make it even easier, try a mini-fast daily. Terry recommends that we stop eating at 7pm and then have breakfast after 7am. Voila-- a 12 hour mini-fast every day that's easy to do. And you'll sleep better without the heavy metabolic action taking place during the night.
This new study also shows that these mini-fasts can help minimize cancer risk.
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