Longevity science

MIT researchers have developed RNA-delivering nanoparticles that allow for rapid screening of new drug targets in mice.

By sequencing cancer-cell genomes, scientists have discovered vast numbers of genes that are mutated, deleted or copied in cancer cells. This treasure trove is a boon for researchers seeking new drug targets, but it is nearly impossible to test them all in a timely fashion.

"Researchers at Harvard-affiliated McLean Hospital have developed a new category of non-toxic, protein-based green nanoparticles that can non-invasively cross the blood brain barrier and transport various types of drugs."

The particles "crossed and/or bypassed the blood-brain barrier without enhancers or modifications, unlike other nanoparticles. These findings open the door to exploring..."