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Highlights
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Ruth Arnon and Michael Sela profoundly influenced the development of a model system to test new therapies in multiple sclerosis.
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By measuring clinical, pathologic, and immunologic outcomes, the biological implications of new drugs could be elucidated.
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The pioneering research on Copaxone using the EAE model, paved the way for the discovery of other therapeutics in MS.
Via Krishan Maggon
Journal of Autoimmunity
Volume 54, November 2014, Pages 1–7
Honoring the contributions of Ruth Arnon and Michael Sela
Review From defining antigens to new therapies in multiple sclerosis: Honoring the contributions of Ruth Arnon and Michael SelaLawrence Steinmana, , Yehuda Shoenfeldb, , , DOI: 10.1016/j.jaut.2014.08.001