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On the Nature of Functional Differentiation: The Role of Self-Organization with Constraints

Ichiro Tsuda, Hiroshi Watanabe, Hiromichi Tsukada, and Yutaka Yamaguti

Entropy 2022, 24(2), 240

The focus of this article is the self-organization of neural systems under constraints. In 2016, we proposed a theory for self-organization with constraints to clarify the neural mechanism of functional differentiation. As a typical application of the theory, we developed evolutionary reservoir computers that exhibit functional differentiation of neurons. Regarding the self-organized structure of neural systems, Warren McCulloch described the neural networks of the brain as being “heterarchical”, rather than hierarchical, in structure. Unlike the fixed boundary conditions in conventional self-organization theory, where stationary phenomena are the target for study, the neural networks of the brain change their functional structure via synaptic learning and neural differentiation to exhibit specific functions, thereby adapting to nonstationary environmental changes. Thus, the neural network structure is altered dynamically among possible network structures. We refer to such changes as a dynamic heterarchy. Through the dynamic changes of the network structure under constraints, such as physical, chemical, and informational factors, which act on the whole system, neural systems realize functional differentiation or functional parcellation. Based on the computation results of our model for functional differentiation, we propose hypotheses on the neuronal mechanism of functional differentiation. Finally, using the Kolmogorov–Arnold–Sprecher superposition theorem, which can be realized by a layered deep neural network, we propose a possible scenario of functional (including cell) differentiation.

Read the full article at: www.mdpi.com


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Cells Blaze Their Own Trails to Navigate Through the Body

Cells Blaze Their Own Trails to Navigate Through the Body | Complexity and Random Overlaps | Scoop.it


With self-generated gradients of chemicals and physical tension, cells in the body steer themselves to vital destinations.

Read the full article at: www.quantamagazine.org


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Phillip Trotter's curator insight, April 1, 2022 6:41 PM

Elena Renken's has written an excellent article  for Quanta Magazine on cell self generated gradients that guide cell migration. There are several implications for modeling and simulating cellular mechanisms and especially cancer cell migration. Very much worthwhile reading and following up on the related research.

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Complex Thinking

New site devoted to supporting the understanding and application of complexity thinking to everyday practices in a broad range of settings.

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What Is a Complex System?

What Is a Complex System? | Complexity and Random Overlaps | Scoop.it
A clear, concise introduction to the quickly growing field of complexity science that explains its conceptual and mathematical foundations

What is a complex system? Although “complexity science” is used to understand phenomena as diverse as the behavior of honeybees, the economic markets, the human brain, and the climate, there is no agreement about its foundations. In this introduction for students, academics, and general readers, philosopher of science James Ladyman and physicist Karoline Wiesner develop an account of complexity that brings the different concepts and mathematical measures applied to complex systems into a single framework. They introduce the different features of complex systems, discuss different conceptions of complexity, and develop their own account. They explain why complexity science is so important in today’s world.

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ideologies and complex systems «

ideologies and complex systems « | Complexity and Random Overlaps | Scoop.it
A recent paper entitled 'A Complex Systems Approach to the Study of Ideology'* presents a theory much like the one I have begun to develop in a series of posts on this blog and other work. The authors write, If we construe ideologies as complex systems, we have (at least) two levels of systems embedded in each other. At the individual level, the elements are ideas, beliefs, and values, whose interactions give rise to a person’s understanding of society, which in turn guides individual political behavior. At the group level, the elements are individual minds whose interactions give rise to

Via june holley
june holley's curator insight, May 11, 2020 7:34 AM

Not "left" and "right" but networks of beliefs. Important for us to understand.

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Addressing climate change post-coronavirus

Addressing climate change post-coronavirus | Complexity and Random Overlaps | Scoop.it
The ongoing crisis holds profound lessons that can help us address climate change post-coronavirus--if we make greater economic and environmental plans for the recovery ahead.

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Global Behaviors and Perceptions in the COVID-19 Pandemic

Fetzer, Thiemo, Marc Witte, Lukas Hensel, Jon Jachimowicz, Johannes Haushofer, Andriy Ivchenko, Stefano Caria, et al. 2020. “Global Behaviors and Perceptions in the COVID-19 Pandemic.” PsyArXiv. April 16. doi:10.31234/osf.io/3kfmh

 

We conducted a large-scale survey covering 58 countries and over 100,000 respondents between late March and early April 2020 to study beliefs and attitudes towards citizens’ and governments’ responses to the COVID-19 pandemic. Most respondents reacted strongly to the crisis: they report engaging in social distancing and hygiene behaviors, and believe that strong policy measures, such as shop closures and curfews, are necessary. They also believe that their government and their country’s citizens are not doing enough and underestimate the degree to which others in their country support strong behavioral and policy responses to the pandemic. The perception of a weak government and public response is associated with higher levels of worries and depression. Using both cross-country panel data and an event-study, we additionally show that strong government reactions correct misperceptions, and reduce worries and depression. Our findings highlight that policy-makers not only need to consider how their decisions affect the spread of COVID-19, but also how such choices influence the mental health of their population.


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Chaos | The Great Courses

Chaos | The Great Courses | Complexity and Random Overlaps | Scoop.it
It has been called the third great revolution of 20th-century physics, after relativity and quantum theory. But how can something called chaos theory help you understand an orderly world? What practical things might it be good for? What, in fact, is chaos theory? "Chaos theory," according to Dr. Steven Strogatz, Director of the Center for Applied Mathematics at Cornell University, "is the science of how things change." It describes the behavior of any system whose state evolves over time and whose behavior is sensitive to small changes in its initial conditions.

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The Foundations of Exponential Impact – John Hagel

The Foundations of Exponential Impact – John Hagel | Complexity and Random Overlaps | Scoop.it
As I’ve spent time exploring these small groups that achieve accelerating impact, I’ve become convinced that they are so important because they help us to address our emotional needs (our heartset) and ultimately to connect with others at a much deeper level (our spiritset) that can cultivate shared passion (specifically, the passion of the explorer). It’s about building deep and enduring (but also evolving) human connection. They do this by achieving a rich balance across dimensions that are often viewed as conflicting.

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Climate tipping points — too risky to bet against

Climate tipping points — too risky to bet against | Complexity and Random Overlaps | Scoop.it

Politicians, economists and even some natural scientists have tended to assume that tipping points in the Earth system — such as the loss of the Amazon rainforest or the West Antarctic ice sheet — are of low probability and little understood. Yet evidence is mounting that these events could be more likely than was thought, have high impacts and are interconnected across different biophysical systems, potentially committing the world to long-term irreversible changes.

Here we summarize evidence on the threat of exceeding tipping points, identify knowledge gaps and suggest how these should be plugged. We explore the effects of such large-scale changes, how quickly they might unfold and whether we still have any control over them.

In our view, the consideration of tipping points helps to define that we are in a climate emergency and strengthens this year’s chorus of calls for urgent climate action — from schoolchildren to scientists, cities and countries.


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Complexity, a podcast by SFI

Far-reaching conversations with a worldwide network of scientists and mathematicians, philosophers and artists developing new frameworks to explain our universe's deepest mysteries. Join host Michael Garfield at the Santa Fe Institute each week to learn about your world and the people who have dedicated their lives to exploring its emergent order: their stories, research, and insights…


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Special Issue: Information Theory for Human and Social Processes

Special Issue: Information Theory for Human and Social Processes | Complexity and Random Overlaps | Scoop.it

Shannon famously applied his “mathematical theory of communication” to human communication, alledgedly having his wife, Betty, estimating word probabilities to calcualte the first approximation of the entropy of English. The following decades have seen creative further applications to humans and social processes (e.g., Miller, 1956; Attneave, 1959; Coleman, 1975; Ellis and Fisher, 1975; Cappella, 1979). These efforts lost steam in the 1980s, mainly because of the lack of adequate data, and limited computational power. Both limitations do not apply anymore. The increase in human interactions taking place in digital environments has led to an abundance of behavioral “big data”, enough even to calculate measures that converge rather slowly.

 

This Special Issue compiles creative research on the innovative uses of information theory, and its extensions, to better understand human behavior and social processes. Among other topics, the focus is set on human communication, social organization, social algorithms, human–machine interaction, artificial and human intelligence, collaborative teamwork, social media dynamics, information societies, digital development, and cognitive and machine biases—all online and/or offline. 


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Complex Learning Made Simple | The Interface

Complex Learning Made Simple | The Interface | Complexity and Random Overlaps | Scoop.it
Santa Fe Institute’s Complexity Explorer lets the public dip into Complexity Science topics.

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How Mathematicians Make Sense of Chaos

How Mathematicians Make Sense of Chaos | Complexity and Random Overlaps | Scoop.it


Dynamical systems can be chaotic and impossible to predict, but mathematicians have discovered tools to help understand them.

Read the full article at: www.quantamagazine.org


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Complexity Research

Complexity Research | Complexity and Random Overlaps | Scoop.it

Where do we come from? Where are we going? New research from the Santa Fe Institute explores key questions related to humanity, society, and the existence of life in our world.

Part 1: The Principles of Complexity: Understanding the Hidden Sources of Order by Dr. Stefani Crabtree

Part 2: Autocatalytic Sets: Complexity at the Interface of Chemistry and Biology by Dr. Wim Hordijk

Part 3: Beyond Pairwise: Higher-Order Interactions in Complex Systems

Read the full article at: www.templeton.org


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Modes of Thinking (in) Complexity. Key Challenges for Theory, Research, and Practice. Satellite Meeting at CCS2021

October 22nd, 2021, ONLINE

This Satellite Meeting takes the form of a workshop aiming to stimulate the discussion and the collaborative co-construction of new ideas about the nature and state of development of the modes of thinking in and for Complexity Studies.

It aims at identifying key challenges and questions that call to be addressed, including those regarding the development of more complex modes of thinking. It will focus the discussion on the identification of key theoretical, empirical, methodological, technical and practical challenges and/or ways of addressing them.

The workshop will aim to identify and explore how these key questions and challenges relate to the development or adaptation of tools and strategies to support the practice of particular modes of thinking in research and practice and to guide real-world interventions and educational activities (formal and informal).

Through a transdisciplinary approach, this meeting aims at constructing and stimulating productive and generative dialogues for the development of more complex modes of thinking (in) Complexity.

More details at: www.complexthinking.org


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Special report: The simulations driving the world’s response to COVID-19

Special report: The simulations driving the world’s response to COVID-19 | Complexity and Random Overlaps | Scoop.it
How epidemiologists rushed to model the coronavirus pandemic.

Via Complexity Digest, june holley
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Chaos | The Great Courses

Chaos | The Great Courses | Complexity and Random Overlaps | Scoop.it
It has been called the third great revolution of 20th-century physics, after relativity and quantum theory. But how can something called chaos theory help you understand an orderly world? What practical things might it be good for? What, in fact, is chaos theory? "Chaos theory," according to Dr. Steven Strogatz, Director of the Center for Applied Mathematics at Cornell University, "is the science of how things change." It describes the behavior of any system whose state evolves over time and whose behavior is sensitive to small changes in its initial conditions.

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Complex Systems Collide, Markets Crash

Complex Systems Collide, Markets Crash | Complexity and Random Overlaps | Scoop.it
At some point, systems flip from being complicated, which is a challenge to manage, to being complex. Complexity is more than a challenge because it opens the door to all kinds of unexpected crashes and events.

Their behavior cannot be reduced to their component parts. It’s as if they take on a life of their own.

Via Complexity Digest
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Science of Stories

Science of Stories | Complexity and Random Overlaps | Scoop.it

Stories have the power to shape our identities and worldviews. They can be factual or fictional, text-based or visual and can take many forms—from novels and non-fiction to conspiracy theories, rumors and disinformation. This Collection includes primary research papers that propose innovative, data-driven approaches to understanding stories and their impact, on such topics as the nature of narrative and narrative thinking, methods to extract stories from datasets and datasets from stories, the role of narrative in science communication, and the transformative power of stories.


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On cycling risk and discomfort: urban safety mapping and bike route recommendations

David Castells-Graells, Christopher Salahub, Evangelos Pournaras

Computing

 

Bike usage in Smart Cities is paramount for sustainable urban development: cycling promotes healthier lifestyles, lowers energy consumption, lowers carbon emissions, and reduces urban traffic. However, the expansion and increased use of bike infrastructure has been accompanied by a glut of bike accidents, a trend jeopardizing the urban bike movement. This paper leverages data from a diverse spectrum of sources to characterise geolocated bike accident severity and, ultimately, study cycling risk and discomfort. Kernel density estimation generates a continuous, empirical, spatial risk estimate which is mapped in a case study of Zürich city. The roles of weather, time, accident type, and severity are illustrated. A predominance of self-caused accidents motivates an open-source software artifact for personalized route recommendations. This software is used to collect open baseline route data that are compared with alternative routes minimizing risk and discomfort. These contributions have the potential to provide invaluable infrastructure improvement insights to urban planners, and may also improve the awareness of risk in the urban environment among experienced and novice cyclists alike.


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Sandy Pentland: The benefits of social physics - BBC Ideas

Sandy Pentland: The benefits of social physics - BBC Ideas | Complexity and Random Overlaps | Scoop.it

MIT's Alex 'Sandy' Pentland explains ‘social physics’ - the analysis of human interactions to improve communities.

Via Complexity Digest, june holley
love story's curator insight, October 17, 2021 6:18 PM

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Complexity science, also called complex systems science, studies how a large collection of components – locally interacting with each other at small scales – can spontaneously self-organize to exhibit non-trivial global structures and behaviors at larger scales, often without external intervention, central authorities or leaders. The properties of the collection may not be understood or predicted from the full knowledge of its constituents alone. Such a collection is called a complex system and it requires new mathematical frameworks and scientific methodologies for its investigation.

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result of a worldwide collaborative effort from leading experts, practitioners and students in the field.

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Rescooped by Liz Rykert from Self-organizing, Systems and Complexity
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Complex Learning Made Simple | The Interface

Complex Learning Made Simple | The Interface | Complexity and Random Overlaps | Scoop.it
Santa Fe Institute’s Complexity Explorer lets the public dip into Complexity Science topics.

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