As is slowly becoming apparent, work from embodied/embedded cognitive science, strongly suggests that to properly understand cognition, studying the “naked” brain will not suffice. Thus, adopting the metaphysics of reductionism as a theoretical cornerstone of one’s framework, is most likely to lead to problems down the line. I think, that the only way for psychiatry to develop is to firstly abandon neurobiological reductionism and embrace an alternative, more holistic metaphysics. Once this is done, then better sense can be made of psychopharmacology and neuroimaging technologies. Until then, I think they will simply continue to mislead the public.