Scientists Identify Interferon-gamma as Potential SARS-CoV-2 Antiviral | NIH: National Institute of Allergy and Infectious Diseases | Virus World | Scoop.it
From www.niaid.nih.gov - December 13, 2023 11:22 AM

Conditioning the lungs with interferon-gamma, a natural immune system protein (cytokine) best known for fighting bacterial infections, appears to be a strong antiviral for SARS-CoV-2, according to National Institutes of Health scientists and colleagues. Their new study, published in Nature Communications, shows in two different mouse models that when a bacterial infection triggers the release of interferon-gamma in the lungs, those animals subsequently are protected from infection by SARS-CoV-2, the virus that causes COVID-19. The investigators further report that using recombinant interferon-gamma in the nose of study mice at the time of viral exposure substantially reduces SARS-CoV-2 infection and COVID disease....

 

Published in Nature Communications (Dec. 2023):

https://doi.org/10.1038/s41467-023-43447-0