Virus World
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Virus World
Virus World provides a daily blog of the latest news in the Virology field and the COVID-19 pandemic. News on new antiviral drugs, vaccines, diagnostic tests, viral outbreaks, novel viruses and milestone discoveries are curated by expert virologists. Highlighted news include trending and most cited scientific articles in these fields with links to the original publications. Stay up-to-date with the most exciting discoveries in the virus world and the last therapies for COVID-19 without spending hours browsing news and scientific publications. Additional comments by experts on the topics are available in Linkedin (https://www.linkedin.com/in/juanlama/detail/recent-activity/)
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Yes, Masks Are Still Necessary - The New York Times

Yes, Masks Are Still Necessary - The New York Times | Virus World | Scoop.it

Short of a total lockdown, universal mask-wearing is the most effective way to slow the relentless rise in hospitalizations and deaths from Covid-19.  As a professional health writer and concerned citizen, the ache in my heart deepens with each new report of the devastation wrought by the novel coronavirus, the cause of immeasurable — and still increasing — personal and economic pain for people caught in its deadly spikes. In a recent five-week period, 100,000 Americans died from complications of Covid-19, a toll that took the country four months to reach last spring. My distress is magnified by the knowledge that it didn’t have to be this bad. One simple measure — consistent wearing of face coverings in public — could have helped to stem the agony. In December, the Centers for Disease Control and Prevention reiterated advice first given in July: “Wear a mask over your nose and mouth. Everyone should wear a mask in public settings and when around people who don’t live in your household, especially when other social distancing measures are difficult to maintain.” Masks, the agency emphasized, protect both the wearer and those the wearer encounters in the course of daily life. Now, with the emergence of a highly contagious variant of the virus and the chaotic attempts to distribute and administer vaccines to hundreds of millions of vulnerable Americans, short of a total lockdown, universal mask-wearing is the most effective way to slow the relentless rise in hospitalizations and deaths from Covid-19.

 

It will take many months to immunize everyone willing and able to get a Covid vaccine. Meanwhile, we’re facing another tsunami of deadly coronavirus infections as the new variant sweeps through swaths of still-unprotected millions As with many other measures not taken by the last administration to minimize the spread of Covid-19, mask-wearing was left up to the states to mandate and enforce. Masks became a political football, and the former president publicly ridiculed opponents who wore them. Some elected officials even made the ridiculous, baseless claim that masks not only don’t thwart the spread of the virus, they actually enhance it. I wonder if they also ignored parents and teachers who told them to cover their mouths when they coughed or sneezed.  I also wonder about the economic savvy of our former president and the governors who have resisted issuing mask mandates, some of whom got Covid-19 themselves yet clamored to open the economy. Goldman Sachs estimated last June that implementing a nationwide mask mandate could have a potential impact on the U.S. GDP of one trillion dollars. Lately, as I await my second vaccine shot, I’ve become increasingly aware of how many people walk, run or cycle without a mask or, if they have a mask, wear it ineffectively. I’ve taken to speaking up more often: “Please wear your mask” or “The mask should cover your nose and mouth.” Among the ignorant responses: “I don’t need a mask when I’m outside,” “I already had Covid so I can’t get it again or give it to you,” and my favorite while walking on a four-foot-wide path, “I stay six feet away from people.” Although six-foot social distancing is not totally arbitrary, it’s based on limited evidence among airline passengers and may not apply at all, for example, to the unmasked cyclists shouting to one another as they ride past me or to the heavy-breathing runners I pass.

 

I’ve also heard a few people say, “I already got the vaccine, so I don’t need a mask.” This may be the most dangerous excuse of all. First, although the vaccines are very good, they’re not perfect, and chances are these vaccine recipients haven’t been checked for strong antibodies to the virus. Second, we don’t yet know if the vaccines, while highly effective in preventing sickness and death, will also prevent asymptomatic infection that can spread the virus to others. As Jeremy Howard, a data scientist at the University of San Francisco, said of mask refusers: “How would you feel if you made your best friend sick, or killed your friend’s mother?” Last February, after the World Health Organization, with no supporting data, advised against wearing a mask unless you were already sick, Mr. Howard amassed an international team of 19 scientists to review the evidence for mask-wearing, expecting to find “that masks were a waste of time,” he said in an interview. Instead, he said, the team found that “the data on the benefit of masks is really compelling.” The results of their exhaustive study were published recently in PNAS, the peer-reviewed Proceedings of the National Academy of Sciences. Mr. Howard said that preliminary reports of their findings resulted “in all sorts of abuse, including death threats” from mask resisters. But that has not kept him from repeating that “wearing any kind of mask will greatly help to keep you from accidentally infecting others, which is important for the community and the economy. About half of coronavirus infections are spread by people who don’t know they’re sick, and the new variant is much more transmissible.”

 

A Chinese study found that the viral load in the upper respiratory tracts of infected people without symptoms can be just as high as those with symptoms, and simply talking and breathing can spread virus-laden droplets and aerosols. And because the virus resides in high amounts in the nose and throat, sneezing can spew an infectious cloud 10 or more times further than coughing. Which brings me to the question of whether the face coverings most people use are sufficiently protective. I now know that the bandannas, exam masks and the slim neoprene masks I’ve been using for the last 11 months are better than nothing but not very good. They provide too many routes for virus-carrying particles to reach an unsuspecting nose or mouth.  I should have followed the advice my colleague Tara Parker-Pope offered months ago on upgrading your mask. “Masks,” Mr. Howard said, “need a nose wire to provide a close fit and proper filtration material, like a nanofiber, that filters very small particles.” He and his co-authors concluded that for most of us, KN95 masks, especially those with bands that fit around the head, are currently the best to prevent contracting and spreading the virus. Another option is the KF94 mask or, if it’s not too uncomfortable, doubling up on masks for added protection. KN95 masks meet foreign certification standards and are designed to filter out 95 percent of particles down to 0.3 microns in size. (The gold standard N95 masks, which meet U.S. certification standards, should be reserved for health care and emergency personnel who are most likely to interact with Covid-infected individuals.) Powecom KN95 masks have an emergency use authorization from the Food and Drug Administration. I just ordered a packet of 11 on Amazon for $23.80 and I expect to be using them for many months after I’m vaccine-protected. I might still be able to transmit the virus and I want to set a good example for my fellow citizens.

 

See also research recently published in PNAS (Jan. 8, 2021):

https://www.pnas.org/content/pnas/118/4/e2014564118.full.pdf 

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COVID-19 Killer: Instant Pot Kills Virus in N95 Mask More Effectively than UV in Under 50 Minutes

COVID-19 Killer: Instant Pot Kills Virus in N95 Mask More Effectively than UV in Under 50 Minutes | Virus World | Scoop.it

Instant Pot proves to be the most effective in sterilizing an N95 mask for reuse and killing the coronavirus compared to ultraviolet light. Yes, you read it right, the 7-in-1 'Instant Pot' used mostly for pressure and slow cooking, rice, and steaming can now be used to disinfect and sterilize an N95 mask killing the Novel coronavirus in less than 50 minutes, experts share. Daily Mail reports that researchers from the University of Illinois found that this kitchen equipment is useful in the kitchen and for other unconventional uses, most notably is its usage for sterilizing an N95 mask. The Instant Pot can disinfect and sterilize a mask, or more, using its standard cook function that runs for 50 minutes. This cook function produces 212 degrees Fahrenheit (100 degrees Celsius) that is said to be enough in killing the virus. Instant Pot uses "dry heat," making it ideal for disinfecting the mask, inside and out. N95 masks use materials including stretchable or garterized materials that lose their flexibility in the span of its use. Researchers list this as one of the concerns of the medical community that frowns on reusing said masks. The effectivity of the mask's filtration significantly reduces if components have reduced performance or functions compared to when it is brand new. This process enables users to safely reuse the mask, unlike the CDC's recommendation of using it for just an extended period. Researchers added that this process is more effective than using an ultraviolet light in sanitation.

 

This home remedy uses the "Instant Pot" that adds a new feature on its long list of functions, including pressure cooking, steaming, rice cooking, slow cooking, sauteing, yogurt making, and warming. Its unique and latest feature, sterilizing the deadly pandemic virus, COVID-19. The University of Illinois researchers exhibited the proper sterilization process in a YouTube video to help the medical community and even people who use the N95 masks for protection against the pandemic. Researchers advise people to put a towel on the Instant Pot's surface to avoid direct heat or contact on the body. The masks only need the heat to go "through and through" to effectively kill any virus, especially COVID-19, that occur the mask's surface and its filters inside. "Any sanitation method would need to decontaminate all surfaces of the respirator, but equally important is maintaining the filtration efficacy and the fit of the respirator to the face of the wearer," Vishal Verma, a researcher of the Insta Pot from the University of Illinois said. The team then tested the mask's fit and deemed that the Instant Pot method helps preserve it. This process helps in decontaminating the mask, maintain its component's integrity to ensure proper fit to the wearer's face, and overall sanitize the product...

 

See also:

https://doi.org/10.1101/2020.07.11.20151399 

https://doi.org/10.1101/2020.07.28.20163915 

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Low-Cost Measurement of Facemask Efficacy for Filtering Expelled Droplets During Speech

Low-Cost Measurement of Facemask Efficacy for Filtering Expelled Droplets During Speech | Virus World | Scoop.it

Mandates for mask use in public during the recent COVID-19 pandemic, worsened by global shortage of commercial supplies, have led to widespread use of homemade masks and mask alternatives. It is assumed that wearing such masks reduces the likelihood for an infected person to spread the disease, but many of these mask designs have not been tested in practice. We have demonstrated a simple optical measurement method to evaluate the efficacy of masks to reduce the transmission of respiratory droplets during regular speech.

 

In proof-of-principle studies, we compared a variety of commonly available mask types and observed that some mask types approach the performance of standard surgical masks, while some mask alternatives, such as neck fleece or bandanas, offer very little protection. Our measurement setup is inexpensive and can be built and operated by non-experts, allowing for rapid evaluation of mask performance during speech, sneezing, or coughing.

 

Original study published in Science Advances (August 7, 2020):

https://doi.org/10.1126/sciadv.abd3083

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Six Steps to Wearing the N95 Mask

N95 masks should be wear while taking care of COVID-19 patients or sharing space or being in the proximity of  confirmed or suspected patients. Use of N95 mask may be recommended in small poorly ventilated public places where you expect to spend long period of times with other unknown persons, including public transportation. The decision to wear N95 masks in these scenarios should be based on the chances of contagion (e.g. expected number of infected people in the area), the risk factors of the user, and the discomfort of having to wear the mask for longer periods of time. N95 masks should not be wear outdoors or while doing exercise, unless the expectation of being in close proximity to infected persons is high. Universal use of common face masks (surgical masks) is more appropriate for outdoor environments.

 

The use of N95 mask increases the effort in breathing and may cause discomfort, tiredness or headache. As some people with chronic lung disease, heart disease or stroke may already have reduced lung volumes or breathing issues, they should stop using a N95 mask if they feel uncomfortable. They should consult their doctor as to whether they can use the N95 mask. The N95 mask is not suitable for pregnant women and children.Persons with chronic lung or heart conditions who feel uncomfortable when wearing the N95 masks should stop doing so and consult a doctor before carrying on.

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