Virus World
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Virus World
Virus World provides a daily blog of the latest news in the Virology field and the COVID-19 pandemic. News on new antiviral drugs, vaccines, diagnostic tests, viral outbreaks, novel viruses and milestone discoveries are curated by expert virologists. Highlighted news include trending and most cited scientific articles in these fields with links to the original publications. Stay up-to-date with the most exciting discoveries in the virus world and the last therapies for COVID-19 without spending hours browsing news and scientific publications. Additional comments by experts on the topics are available in Linkedin (https://www.linkedin.com/in/juanlama/detail/recent-activity/)
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Babies Exposed to COVID in the Womb Are More Likely to Suffer Breathing Problems - Scientific American

Babies Exposed to COVID in the Womb Are More Likely to Suffer Breathing Problems - Scientific American | Virus World | Scoop.it

Infants born to people who had COVID while pregnant are at a higher risk of respiratory distress, but vaccination greatly lowers the risk. More than four years after the virus that causes COVID first appeared, scientists continue to discover new ways that the illness threatens pregnant people and babies—as well as additional evidence that vaccination offers significant protection. A new study finds that babies born to women who got COVID while they were pregnant were three times more likely to develop serious breathing problems than infants whose mothers didn’t have the disease during pregnancy, even if the infants weren’t infected themselves. Seventeen percent of the babies in the study who were exposed to COVID before birth developed respiratory distress, compared with only about 5 to 6 percent of newborns in the general population before the pandemic. The findings were published on Wednesday in Nature Communications....

 

Stucy cited (Jan. 24, 2023):

https://doi.org/10.1038/s41467-023-44549-5 

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Covid-19 Vaccines Provide Protection for Pregnant and Lactating Women, and Their Newborns

Covid-19 Vaccines Provide Protection for Pregnant and Lactating Women, and Their Newborns | Virus World | Scoop.it

The Pfizer/BioNTech and Moderna Covid-19 vaccines are effective in pregnant and lactating women, who can pass protective antibodies to newborns, according to research published Thursday in the American Journal of Obstetrics and Gynecology. Researchers at Massachusetts General Hospital, Brigham and Women's Hospital and the Ragon Institute of MGH, MIT and Harvard looked at 131 women who received either the Pfizer/BioNTech or Moderna Covid-19 vaccine. Among the participants, 84 were pregnant, 31 were lactating and 16 were not pregnant. Samples were collected between December 17, 2020 and March 2, 2021.  The vaccine-induced antibody levels were equivalent in pregnant and lactating women, compared to non-pregnant women. The antibody levels were "strikingly higher" than those resulting from coronavirus infection during pregnancy, the team noted. "These vaccines seem to work incredibly effectively in these women," said one of the researchers, Galit Alter, a professor of medicine at the Ragon Institute.

 

In addition, the team found that women passed protective antibodies to their newborns, measured in breast milk and the placenta. "Nearly all the moms were getting a pretty decent level of antibodies to their babies," said Alter, who added that additional research is needed to understand how long those protective antibodies last in newborns.  Participants used the US Centers for Disease Control and Prevention's V-safe tool, which allows people who have received a Covid-19 vaccine to track their reaction. Alter said they found no evidence of more side effects or more intense side effects in pregnant and lactating women than in the general population. While the team found similar antibody levels in women vaccinated with both vaccines, Alter said they found higher levels of IgA antibodies in pregnant women who received the Moderna vaccine. She said this particular type of antibody may be transferred more efficiently to babies, for a longer period of time. "There is some reason to think that having higher levels of IgA immunity might be more protective," Alter noted. She said additional research into this finding could help inform policy decisions about which vaccines are used for pregnant populations. Recent research similarly found that mRNA vaccines illicit antibodies in pregnant women that can be transferred to their babies, though this is the largest study on vaccines in pregnant women, to date. Pregnant and lactating women were not included in the initial clinical trials of the vaccines.
 
With no data to look to help inform pregnant women's decisions about getting vaccinated against Covid-19, Alter said researchers and new and expectant mothers -- particularly health care workers -- stepped up to fill the void. "MGH and Brigham started to talk to the health care workers that were eligible for vaccination, that were also pregnant, and they created a study to empower pregnant women with the ability to track their responses, but to also develop data that could essentially help the entire globe approach vaccination and pregnancy for the first time in this collective kind of way.  "It was really just a force to be reckoned with, both from the OB-GYN/provider perspective, but also from the community," said Alter. "It was inspiring." According to the CDC, pregnant people with Covid-19 are at increased risk for severe illness and may be at increased risk for adverse outcomes, like preterm birth. The CDC says it hopes to study vaccine safety in around 13,000 pregnant people for each of the three authorized coronavirus vaccines. The agency will use a specific V-safe pregnancy registry, which had enrolled about 3,612 pregnant women, as of March 22. "This is an urgent need, because we're not only protecting one person in this vaccine effort, we're protecting two people at the same time," said Alter.
 
 
kaylarcampbell79@gmail.com's curator insight, July 16, 2021 11:42 PM
It is good to see that pregnant women are protected. i know for many women that was a scare will it effect my unborn baby or will ir effect my chances of pregnancy in the future. Two extremley important questions to be ask as a women who is either planning or is pregnant.