This study examines differences in microbial colonization and community stability in PID skin and informs our understanding of host–microbiome interactions, suggesting a bidirectional dialogue between skin commensals and the host organism.
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The altered landscape of the human skin microbiome in patients with primary immunodeficienciesJulia Oh1, Alexandra F. Freeman2, NISC Comparative Sequencing Program3, Morgan Park3, Robert Sokolic1, Fabio Candotti1,Steven M. Holland2, Julia A. Segre1,5,6 and Heidi H. Kong4,5,6Article published online before print. Article, supplemental material, and publication date are athttp://www.genome.org/cgi/doi/10.1101/gr.159467.113.