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The world's first cancer vaccine has halved the number of new cervical cancers ten years after it was first administered in Australia. 
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Scoop.it!
Available credits for clinical personel
Clinical Context Human papillomavirus (HPV) is the most commonly detected sexually transmitted organism in women. It is responsible for cervical cancer in women, as well as other anogenital cancers and genital warts in both men and women. In June 2006, the US Food and Drug Administration approved the HPV vaccine for females aged 9 to 26 years for the prevention of cervical cancer. However, more recently, the recommendations for quadrivalent HPV vaccine was expanded to females aged 9 to 26 for prevention of vaginal and vulvar cancer, men aged 9 to 26 years for prevention of genital warts, and females and males aged 9 to 26 years old for prevention of anal intraepithelial neoplasia and anal cancer. The quadrivalent human papillomavirus vaccine has been known to be safe, well tolerated, and highly immunogenic. The aim of this study by Klein and colleagues was to assess the safety of the quadrivalent HPV vaccine in females after routine administration.
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Jennifer W. Leiding, MD,Steven M. Holland, MD Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md Received 23 March 2012; received in revised form 6 June 2012; accepted 25 July 2012. published online 02 October 2012.
Infection with human papillomavirus (HPV) is almost universal and eventually asymptomatic, but pathologic infection with HPV is severe, recurrent, and recalcitrant to therapy. It is also an underappreciated manifestation of primary immunodeficiency. Mutations in EVER1, EVER2, GATA2, CXCR4, and dedicator of cytokinesis 8 (DOCK8) are typically associated with extensive HPV infections, whereas several other primary immune defects result in severe HPV much less frequently. We review immunodeficiencies with severe HPV infections and the mechanisms underlying them.
pdf article: http://download.journals.elsevierhealth.com/pdfs/journals/0091-6749/PIIS0091674912012973.pdf
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Cervical cancers have been cutted down by half since the HPV vaccine was first introduced. That is a real new and a real knowledge all the population should know.