Immunopathology & Immunotherapy
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Immunopathology & Immunotherapy
Latest advances in immunopathology diagnosis and treatment
Curated by Alfredo Corell
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A bad alliance: Rare immune cells promote food-induced allergic inflammation in the esophagus

A bad alliance: Rare immune cells promote food-induced allergic inflammation in the esophagus | Immunopathology & Immunotherapy | Scoop.it
PHILADELPHIA – Food is an integral part of life; but, for some, it can be harmful. Allergic inflammation caused by inappropriate immune responses to some types of food has become a major public health issue.
Alfredo Corell's insight:
Thymic stromal lymphopoietin–elicited basophil responses promote eosinophilic esophagitisMario Noti,Elia D Tait Wojno,Brian S Kim,Mark C Siracusa,Paul R Giacomin,Meera G Nair,Alain J Benitez,Kathryn R Ruymann,Amanda B Muir,David A Hill,Kudakwashe R Chikwava,Amin E Moghaddam,Quentin J Sattentau,Aneesh Alex,Chao Zhou,Jennifer H Yearley,Paul Menard-Katcher,Masato Kubo,Kazushige Obata-Ninomiya,Hajime Karasuyama,Michael R Comeau,Terri Brown-Whitehorn,Rene de Waal Malefyt,Patrick M Sleiman,Hakon Hakonarsonet al.

Link to Nature Medicine Paper: http://www.nature.com/nm/journal/vaop/ncurrent/full/nm.3281.html

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Protocolos de Inmunología Clínica y Alergología | Asociación Española de Pediatría

Protocolos de Inmunología Clínica y Alergología | Asociación Española de Pediatría | Immunopathology & Immunotherapy | Scoop.it
Alfredo Corell's insight:

Buena colección de protocolos diagnósticos en patologías alergicas

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Systemic reactions from allergy skin testing: 0.4% for skin prick testing, 3.2% for intradermal

Systemic reactions from allergy skin testing: 0.4% for skin prick testing, 3.2% for intradermal | Immunopathology & Immunotherapy | Scoop.it

Systemic reactions from allergy skin testing: 0.4% for skin prick testing, 3.2% for intradermal

Skin testing is the diagnostic cornerstone for allergies and is considered extremely safe, carrying only a small risk of systemic reactions.

A prospective study included 1,500 patients at the University of South Florida and aimed to determine the 12-month incidence of systemic reactions (SRs) to skin prick testing (SPT) and intradermal skin testing (ST). Epinephrine (0.2 mL of a 1:1,000 dilution) was administered intramuscularly in the deltoid as soon as any remote signs or symptoms occurred.

Yotam Levin's curator insight, August 2, 2015 12:53 PM

Interesting data for allergists to consider..

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Programa científico - Alergia e Inmunología Clínica - Pamplona SEAIC 2012

Programa científico - Alergia e Inmunología Clínica - Pamplona SEAIC 2012 | Immunopathology & Immunotherapy | Scoop.it

Programa Científico del XXVIII Congreso de la Sociedad Española de Alergia e Inmunología Clínica (SEAIC)

Pamplona, 17-20 octubre de 2012

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Journal of Allergy and Clinical Immunology - Home

Journal of Allergy and Clinical Immunology - Home | Immunopathology & Immunotherapy | Scoop.it
After one year, studies published in the Journal of Allergy and Clinical Immunology are available free of charge.

Via Gilbert C FAURE
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:::Comité de Aerobiología:::

:::Comité de Aerobiología::: | Immunopathology & Immunotherapy | Scoop.it

Comite de Aerobiología Sociedad Española de Alergología e Inmunología Clínica... RECUENTOS DE PÓLENES POR PROVINCIAS

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Hypersensitivity reactions Reading Hypersensitivity reactions – Star - Hi Books

Breves apuntes (ingles) sobre los tipos de reacciones de Hipersensibilidad

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Schnitzler's syndrome: diagnosis, treatment, and follow-up - Simon - 2013

Schnitzler's syndrome: diagnosis, treatment, and follow-up - Simon - 2013 | Immunopathology & Immunotherapy | Scoop.it

ALLERGY

Review Article

You have free access to this contentSchnitzler's syndrome: diagnosis, treatment, and follow-upA. Simon1,B. Asli2,M. Braun-Falco3,H. De Koning4,J.-P. Fermand2,C. Grattan5,K. Krause6,H. Lachmann7,C. Lenormand8,V. Martinez-Taboada9,M. Maurer6,M. Peters10,R. Rizzi11,F. Rongioletti12,T. Ruzicka3,L. Schnitzler13,B. Schubert14,J. Sibilia15,D. Lipsker8

Article first published online: 9 MAR 2013

DOI: 10.1111/all.12129

Alfredo Corell's insight:

Schnitzler's syndrome is characterized by recurrent urticarial rash and monoclonal gammopathy, associated with clinical and biological signs of inflammation and a long-term risk of AA amyloidosis and overt lymphoproliferation.

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Probiotics help manage of allergy during pollen seasons

Probiotics help manage of allergy during pollen seasons | Immunopathology & Immunotherapy | Scoop.it
A daily dose of Nestlé’s Bifidobacterium lactis NCC2818 probiotic strain may help manage allergic responses during pollen season, says a new study from the Nestlé Research Center.
Alfredo Corell's insight:

Very interesting paper. I think that whatever nutritional natural complement is always better than any new pill to take.

 

Link to the European Journal of Clinical Nutrition original publication:

www.nature.com/ejcn/journal/vaop/ncurrent/abs/ejcn2012197a.html

 

Original Article

European Journal of Clinical Nutrition advance online publication 9 January 2013; doi: 10.1038/ejcn.2012.197

Immune-modulatory effect of probiotic Bifidobacterium lactis NCC2818 in individuals suffering from seasonal allergic rhinitis to grass pollen: an exploratory, randomized, placebo-controlled clinical trial

A Singh1, F Hacini-Rachinel1,4, M L Gosoniu2, T Bourdeau1, S Holvoet1, R Doucet-Ladeveze1, M Beaumont3, A Mercenier1 and S Nutten1

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The Anisakis allergy debate: does an evolutionary approach help? (Trends in Parasitology )

The Anisakis allergy debate: does an evolutionary approach help? (Trends in Parasitology ) | Immunopathology & Immunotherapy | Scoop.it

Trends in Parasitology

Volume 28, Issue 1, January 2012, Pages 9–15

Alvaro Daschner, ,Carmen Cuéllar,Marta Rodero

Servicio de Alergia, Instituto de Investigación Sanitaria, Hospital Universitario de la Princesa, Madrid, Spain

Departamento de Parasitología, Facultad de Farmacia, Universidad Complutense, Madrid, Spain

http://dx.doi.org/10.1016/j.pt.2011.10.001,

 

Allergic phenomena share common pathways with the immune response against helminth parasites. The definitions regarding allergens and their related concepts have their roots in the area of allergy research. The experience with the fish parasite Anisakis simplex-associated allergic features still nurtures an open debate on the necessity of larvae being alive to induce allergic reactions such as urticaria or anaphylaxis. Conceptual definitions of allergen, major allergen, as well as putatively crossreacting antibodies, as are used in food allergy, depend on the clinical relevance of specific IgE and deserve careful interpretation in the various forms of A. simplex-associated allergic features. Conversely, an evolutionary based interpretation of the presence of specific IgE depends on the viability of A. simplex.

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Genetically engineered cow yields hypoallergenic, high-protein milk

Genetically engineered cow yields hypoallergenic, high-protein milk | Immunopathology & Immunotherapy | Scoop.it

"Targeted microRNA expression in dairy cattle directs production of β-lactoglobulin-free, high-casein milk," by Anower Jabed, et al.
10.1073/pnas.1210057109

 

More information:

http://www.cnn.com/2012/10/01/health/genetically-modified-hypoallergenic-milk/index.html

 

http://www.20minutos.es/noticia/1604738/0/daisy/vaca-clonada/alergia-leche/

 

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157 DISEASES OF IMMEDIATE TYPE HYPERSENSITIVITY « Free ...

157 DISEASES OF IMMEDIATE TYPE HYPERSENSITIVITY « Free ... | Immunopathology & Immunotherapy | Scoop.it
157 DISEASES OF IMMEDIATE TYPE HYPERSENSITIVITY Harrison's Manual of Medicine. 157. DISEASES OF IMMEDIATE TYPE HYPERSENSITIVITY. Urticaria and Angioedema Allergic Rhinitis Systemic Mastocytosis ...
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Allergy Notes: Untangling asthma phenotypes and endotypes

Allergy Notes: Untangling asthma phenotypes and endotypes | Immunopathology & Immunotherapy | Scoop.it

Allergy, Asthma and Immunology News Updated Daily by Board-certified Allergists and Assistant Professors at University of Chicago and NSU

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