‘Next-generation’ antibodies could complement current therapies.
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Immunopathology & Immunotherapy
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Latest advances in immunopathology diagnosis and treatment
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Alfredo Corell
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Two papers published online today in Nature1, 2 report the impact of antibody therapy on an HIV-related virus that is capable of infecting monkeys and was engineered to carry key portions of the genome of the human virus. Levels of that modified virus, called SHIV, plummeted after the macaques were infused with human antibodies isolated from HIV patients and selected for their potency against a broad array of HIV viruses.
Barouch, D. H. et al. Nature doi:10.1038/nature12744 (2013).
Shingai, M. et al. Nature doi:10.1038/nature12746 (2013).