Immunopathology & Immunotherapy
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Immunopathology & Immunotherapy
Latest advances in immunopathology diagnosis and treatment
Curated by Alfredo Corell
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Severe South American Ocular Toxoplasmosis Is Associated with Decreased Ifn-γ/Il-17a and Increased Il-6/Il-13 Intraocular Levels

Severe South American Ocular Toxoplasmosis Is Associated with Decreased Ifn-γ/Il-17a and Increased Il-6/Il-13 Intraocular Levels | Immunopathology & Immunotherapy | Scoop.it

Alejandra de-la-Torre,Arnaud Sauer,Alexander W. Pfaff,Tristan Bourcier, Julie Brunet,Claude Speeg-Schatz,Laurent Ballonzoli,Odile Villard,Daniel Ajzenberg,Natarajan Sundar,Michael E. Grigg,Jorge E. Gomez-Marin equal contributor,Ermanno Candolfi equal contributor mail

Alfredo Corell's insight:

Ocular toxoplasmosis (OT), due to protozoan parasite Toxoplasma gondii, is a potential complication of both acquired and congenital infection, leading to visual impairment in numerous countries and being responsible for 30 to 50% of uveitis cases in immunocompetent individuals. In this study we confirmed the presence of more severe ocular toxoplasmosis in a tropical setting of Colombia, when compared to France. The main hypothesis for these clinical differences is based on the idea that severe disease in humans may result from poor host adaptation to neotropical zoonotic strains of T. gondii Indeed, our results are consistent with the hypothesis that South American strains may cause more severe OT due to an inhibition of the intraocular protective immune response.

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Keratomycosis – also called Fungal Keratitis - IMAGES

Keratomycosis – also called Fungal Keratitis - IMAGES | Immunopathology & Immunotherapy | Scoop.it

Keratitis is the general medical term used to describe an inflammation that occurs in the cornea of the eye.Corneal inflammations can be caused by various agents, notably bacterial, fungal or viral – but whatever the agent the cornea is going to present some quite nasty symptoms.

Keratomycosis is the name reserved for keratitis initiated by a fungus.

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IOBA-InmunoLAB (Infectious and immune-mediated ophtalmic disease diagnosis) last tests update

IOBA-InmunoLAB (Infectious and immune-mediated ophtalmic disease diagnosis) last tests update | Immunopathology & Immunotherapy | Scoop.it

For any questioun, doubt, english documents or enqueries: .

 


DIAGNOSTIC TESTS FOR:
-Ophtalmic infections
-Ophtalmic inflammation
-Ophtalmic diseases genetics,
-Immune-mediated ocular inflammation

Laboratorio de Inmunología (inmunoLAB)
Edificio IOBA, Campus Miguel Delibes
Paseo de Belén 17
47011 Valladolid
E-mail: inmunolab@ioba.med.uva.es
Tel: (+34) 983 423238 / 983 184755


Via Alfredo Corell
Alfredo Corell's insight:

Feel free of asking any question or make any suggestion.

Alfredo Corell's curator insight, September 8, 2013 11:34 AM

Any sample (biopsies, brush or impresion cytologies, corneal scraping, vitreous or aqueus humour, ....)

DIAGNOSTIC TESTS FOR:
-Ophtalmic infections
-Ophtalmic inflammation
-Ophtalmic diseases genetics,
-Immune-mediated ocular inflammation

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Ranibizumab (anti-VEGF) in the treatment of Macular Degeneration

Ranibizumanb in the treatment of the Macular Degeneration.

A complete 3D video showing the mechanism of the disease and the action of the Monoclonal Antibodie.

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