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fascinating review of costimulatory pathway drugs in inflammation & autoimmunity... did bench work on many of these! http://t.co/sPaZK8nR9d
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Scooped by Alfredo Corell |
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Nature Reviews Nephrology 10, 14-24 (2014) doi:10.1038/nrneph.2013.183
Ultimately, understanding the interplay between individual co-stimulatory and co-inhibitory pathways engaged during T-cell activation and
differentiation will lead to rational and targeted therapeutic interventions to manipulate T-cell responses and improve clinical outcomes.