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A new vaccine has been developed to act as a booster to Bacille Calmette Guerin (BCG), currently the only TB vaccine available. BCG was developed in the 1920s and has been used worldwide.
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Scooped by Alfredo Corell |
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Link to the Science Translational Medicine publication:
http://stm.sciencemag.org/content/5/205/205ra134
Sci Transl Med 2 October 2013:Vol. 5, Issue 205, p. 205ra134
Sci. Transl. Med. DOI: 10.1126/scitranslmed.3006843A Human Type 5 Adenovirus–Based Tuberculosis Vaccine Induces Robust T Cell Responses in Humans Despite Preexisting Anti-Adenovirus ImmunityFiona Smaill1,2, Mangalakumari Jeyanathan1,3, Marek Smieja1,2, Maria Fe Medina1,3,Niroshan Thanthrige-Don1,3, Anna Zganiacz1,3, Cindy Yin1,3, Armando Heriazon1,3,Daniela Damjanovic1,3, Laura Puri1, Jemila Hamid1,4, Feng Xie4, Ronan Foley1,3,Jonathan Bramson1,2,3, Jack Gauldie1,2,3 and Zhou Xing1,2,3,*