Immunopathology & Immunotherapy
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Immunopathology & Immunotherapy
Latest advances in immunopathology diagnosis and treatment
Curated by Alfredo Corell
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Cómo ‘resetear’ el sistema inmune para curar una enfermedad

Cómo ‘resetear’ el sistema inmune para curar una enfermedad | Immunopathology & Immunotherapy | Scoop.it
Un tratamiento experimental logra revertir el sistema inmunológico y curar a pacientes con enfermedad de Crohn
Alfredo Corell's insight:

Azucena Salas incide en el equilibrio entre esperanzas y riesgos: “Ver con tus propios ojos casos de recuperación completa como el de Javier es ilusionante. Los datos confirman que podemos resetear el sistema inmunológico de pacientes con enfermedades autoinmunes, lo cual es muy esperanzador. Pero advertirles de que hay riesgo de muerte es muy duro, y sólo merece la pena en casos muy concretos en que sepamos que la terapia va a funcionar. Debemos seguir investigando”.

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Fecal Microbiota Transplantation in Ulcerative Colitis

Fecal Microbiota Transplantation in Ulcerative Colitis | Immunopathology & Immunotherapy | Scoop.it
CONCLUSIONS:

 This study highlights the value of characterizing temporally resolved microbiota dynamics for a better understanding of FMT efficacy and provides potentially useful diagnostic indicators for monitoring FMT success in the treatment of ulcerative colitis.

Alfredo Corell's insight:

Am J Gastroenterol 2013; 108:1620–1630; doi:10.1038/ajg.2013.257; published online 24 September 2013

Temporal Bacterial Community Dynamics Vary Among Ulcerative Colitis Patients After Fecal Microbiota Transplantation

Sieglinde Angelberger MD1, Walter Reinisch MD1, Athanasios Makristathis PhD2, Cornelia Lichtenberger1, Clemens Dejaco MD1, Pavol Papay MD1, Gottfried Novacek MD1, Michael Trauner MD1, Alexander Loy PhD3 and David Berry PhD3

 

Divulgative resumen: http://medicalxpress.com/news/2013-09-microbial-inflamed-gut.html

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KEY ADVANCES IN MEDICINE by Nature Reviews journals

KEY ADVANCES IN MEDICINE by Nature Reviews journals | Immunopathology & Immunotherapy | Scoop.it
Alfredo Corell's insight:

Including Immunology (pathology and therapies) topics:


  • 29 TYpE 2 DiAbETES MElliTUS | A central role of the gut in glucose homeostasis; Geltrude Mingrone and Lidia Castagneto-Gissey
  • 30 METAbOliSM | The gut microbiota manages host metabolism; Patrice D. Cani
  • 35 hEpATiTiS C | HCV causes systemic disorders that can be cured; Francesco Negro
  • 37 fAECAl MiCRObiOTA TRANSplANTATiON | Developing human gut microbiota as a class of therapeutics; Alexander Khoruts
  • 38 COEliAC DiSEASE | New insights in dietary-gluten-induced autoimmunity; Katri Kaukinen and Markku Mäki
  • 42 ibD | Enriching the therapeutic armamentarium for IBD;  Silvio Danese and Laurent Peyrin-Biroulet
  • 51 TRANSplANTATiON iMMUNOlOgY | New approaches to diagnosis of rejection; Nicholas A. Zwang and Laurence A. Turka
  • 65 MUlTiplE SClEROSiS | Novel triggers, treatment targets and brain atrophy measures; Xavier Montalban and Mar Tintoré
  • 71 SYSTEMiC lUpUS ERYThEMATOSUS | Taking a closer look at biologic therapy for SLE; David A. Isenberg and Anisur Rahman
  • 72 EpigENETiCS | DNA methylation and miRNA—key roles in systemic autoimmunity; Bruce C. Richardson and Dipak R. Patel
  • 74 RhEUMATOiD ARThRiTiS | Translational medicine in RA—time for change; Pierre Miossec


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