Rueda de prensa de Gregory Winter y Richard Lerner.
Reciben el premio príncipe de asturias de 2012 por sus importantes descubrimientos para el desarrollo de los anticuerpos monoclonales "humanizados" y su uso en el tratamiento de patologías.
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Immunopathology & Immunotherapy
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Latest advances in immunopathology diagnosis and treatment
Curated by
Alfredo Corell
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Scoop.it!
Anti-cytokine vaccination is an innovative strategy of targeted, active immunotherapy with potential application in autoimmune diseases. The principle is to design molecules capable of triggering a humoral immune response versus a cytokine with a recognized pathogenic role in a given disease. The most used vaccination approach is based on self-protein coupled to a carrier. This strategy proved particular efficacy in models of TNF-α-dependent diseases, and promising results come from recent clinical trials in rheumatoid arthritis and Crohn's disease. The benefit/risk ratio and long term safety of anti-cytokine vaccination need to be determined to further develop this therapeutic strategy. 
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