Immunopathology & Immunotherapy
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Immunopathology & Immunotherapy
Latest advances in immunopathology diagnosis and treatment
Curated by Alfredo Corell
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Scooped by Alfredo Corell
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Vitamin A used in acne medicines may help autoimmune and transplant patients

Vitamin A used in acne medicines may help autoimmune and transplant patients | Immunopathology & Immunotherapy | Scoop.it
Vitamin A used in acne medicines may help autoimmune and transplant patients Science Codex "The results will help us to use the different protocol of Treg induction for clinical therapy in autoimmune diseases and organ transplantation protection,'"...
Alfredo Corell's insight:

The original research article is published in The Journal of Leukocyte Biology:

http://www.jleukbio.org/content/95/2/275.full 

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Scooped by Alfredo Corell
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NIH scientists find link between allergic and autoimmune diseases in mouse study

NIH scientists find link between allergic and autoimmune diseases in mouse study | Immunopathology & Immunotherapy | Scoop.it
Scientists at the National Institutes of Health, and their colleagues, have discovered that a gene called BACH2 may play a central role in the development of diverse allergic and autoimmune diseases,...
Alfredo Corell's insight:
BACH2 represses effector programs to stabilize Treg-mediated immune homeostasisRahul Roychoudhuri,Kiyoshi Hirahara,Kambiz Mousavi,David Clever,Christopher A. Klebanoff,Michael Bonelli,Giuseppe Sciumè,Hossein Zare,Golnaz Vahedi,Barbara Dema,Zhiya Yu,Hui Liu,Hayato Takahashi,Mahadev Rao,Pawel Muranski,Joseph G. Crompton,George Punkosdy,Davide Bedognetti,Ena Wang,Victoria Hoffmann,Juan Rivera,Francesco M. Marincola,Atsushi Nakamura,Vittorio Sartorelli,Yuka KannoNature(2013)doi:10.1038/nature12199Link to Nature publication: http://www.nature.com/nature/journal/vaop/ncurrent/full/nature12199.html
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Rescooped by Alfredo Corell from Multiple sclerosis New Drugs Review
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Regulatory T cell proliferative potential is impaired in human autoimmune disease

Regulatory T cell proliferative potential is impaired in human autoimmune disease | Immunopathology & Immunotherapy | Scoop.it
Here we report that proliferation of Treg cells after TCR stimulation is impaired in subjects with relapsing-remitting multiple sclerosis (RRMS) because of altered interleukin-2 (IL-2) secretion and IL-2 receptor (IL-2R)-signal ...

Via Krishan Maggon
Alfredo Corell's insight:

Original article:

http://www.nature.com/nm/journal/vaop/ncurrent/full/nm.3411.html

NATURE MEDICINE | LETTER 

Regulatory T cell proliferative potential is impaired in human autoimmune diseaseFortunata Carbone,Veronica De Rosa,Pietro B Carrieri,Silvana Montella,Dario Bruzzese,Antonio Porcellini,Claudio Procaccini,Antonio La Cava& Giuseppe Matarese
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